Products

SMAs

The following purified SMAs are currently available. Click the highlighted designation links to download PDF datasheets.

Materials safety data sheet

Information and samples for evaluation

Thyroid

Reactivity

Description

Designation

Tri-iodothyroxine (T3)

Useful for ultra-sensitive detection of free-T3 (FT3)

T3.17C6r

Thyroxine (T4)

For thyroid function tests Bind many commercially available T4 conjugates

T4.1C4

Thyroid Stimulating Hormone (TSH)

Epitope 1. Forms part of the thyroid function testing panel.

TSH.1H11, TSH.6C10

Epitope 2. Can pair with other TSH Abs.

TSH.6C9, TSH.11H5, TSH.12C7

Epitope 3

TSH.4C3

Epitope 4

TSH.6F11

Parathyroid Hormone

Binds the N-terminal PTH and the biologically active PTH

PTH.3E8 (N-terminal aa1-6)

Binds mid-molecule PTH. Epitope is different to PTH.1D4.

PTH.1B9 (Mid-region aa44-68)

Binds mid-molecule PTH. Can pair with PTH.1B9.

PTH.1D4 (Mid-region aa44-68)

Binds to C-terminal PTH. Pairs well with PTH.3E8.

PTH.3B8 (C-terminal aa64-84)

Vitamin D

Reactivity

Description

Designation

25-Hydroxy D2

Binds 25-Hydroxy vitamin D2 conjugates

VitD2.2D10

25-Hydroxy D3

Binds 25-Hydroxy vitamin D3 conjugates

VitD3.2F4

Total 25-Hydroxy D2+D3

Binds 25(OH) D2/D3 equally. Useful for total vitamin D testing in serum or plasma.

VitD3.5H10

Cardiac

Reactivity

Description

Designation

Brain Natriuretic Peptide

Binds region bounded by amino acids 10-26, “loop”

BNP.3E7

Binds C-terminus amino acids 27-32

BNP.4H8

Drugs of abuse

Reactivity

Description

Designation

Tetrahydrocannabinol (THC)

Useful for detecting cannabis use

THC.5B7

Binds THC in oral fluids

THC.2B9

Buprenorphine

Useful in monitoring treatment with buprenorphine for opioid addiction

BUP.1C5

Most sensitive detection of buprenorphine and metabolites in saliva

BUP.3G11

Benzodiazepines

Measurement of ‘benzos’ is useful as part of general drugs of abuse screening

benzo.10G10 and others

Ethyl Glucoride (EtG)

Used for alcohol abuse monitoring

EtG.1E6

Fertility

Reactivity

Description

Designation

Estrone (E1)

Useful to monitor low-dose female hormone replacement therapy in postmenopausal women. Useful to reduce undesirable estrone cross-reactivity in E2 assays.

E1.3H11r

Estradiol (E2)

Useful to investigate menstrual abnormalities. Estrone cross-reactivity can be blocked by E1.3H11.

E2.5A11

E2.2C7

Has low estrone cross-reactivity

E2.6H9

Estriol (E3)

Useful in second trimester monitoring in pregnancy

E3.8A4

E3.12G3

Progesterone

Useful for fertility monitoring. Prog.3H3 has been raised against a prog-11-BSA conjugate.

Prog.3H3

Testosterone

Excellent sensitivity and precision in testosterone detection in both men and women

Testo3.6A3

Androstenedione

Suitable for monitoring androstenedione levels in females

Andro.3C3

Adrenocorticotropic Hormone

Useful for detecting adrenal insufficiency

ACTH.8A11 (N-term)

Binds to cosyntropin

ACTH.7E7 (Middle)

Binds the CLIP region of ACTH

ACTH.9F7 (C-term)

Oncology

Reactivity

Designation

Human Chorionic Gonadotrophin (hCG)

hCG.11E7

hCG.4F9, hCG.8F11

hCG.12F6

Miscellaneous

Reactivity

Description

Designation

D-biotin

Binds to biotin with super-high affinity similar to avidin-biotin

DBt.1D10

L-biotin

Binds the Laevo form of biotin. No interference by endogenous D-biotin.

LBt.1A7

Cortisol

Binds cortisol and is used in tests to diagnose Cushing’s syndrome and Addison’s disease

cort.8F4

Sheep FAb

Mouse monoclonal antibody (muMAb) binds to sheep FAb

ShFAb.1H6